Oxandrolone is also a 17alpha alkylated oral steroid , carrying an alteration that is noted for putting stress on the liver. It is important to point out however that to spite this alteration this drug is generally very well tolerated. While liver enzyme tests will occasionally show elevated values, actual damage due to Oxandrolone is not a statistical problem. Bio-Technology General states that this substance is not as extensively metabolized by the liver as other 1 7aa orals are; evidenced by the fact that nearly a third of product is still intact when excreted in the urine. This may have to do with the understood mHder nature of Oxandrolone (compared to other 1 7aa orals) in terms of hepatotoxicity. One study comparing the effects of Oxandrolone to other agents including as methyltestosterone, norethandrolone, fluoxymesterone and methandriol clearly supports this notion. Here it was demonstrated that the steroid causes the lowest sulfobromophthalein (BSP; a marker of liver stress) retention among all the alkylated orals tested. 20mg of Oxandrolone in fact produced 72% less BSP retention than an equal dosage of fluoxymesterone, which is a considerable difference being that they possess the same liver-toxic alteration. With such findings, combined with the fact that athletes rarely report trouble with Oxandrolone, most feel comfortable believing it to be much safer to use during longer cycles than most of other orals with this distinction. Although this may very well be true, the chance of liver damage still cannot be excluded however.
Other abilities of Oxandrolone
At one time Oxandrolone was also looked at as a possible drug for those suffering from disorders of high cholesterol or triglycerides. Early studies showed that substance to be capable of lowering total cholesterol and triglyceride values in certain types of hyperlipidemic patients, which initially this was thought to signify potential for Oxandrolone as a hypo-lipid (lipid lowering) agent. With further investigation we find however that while use of this steroid can be linked to a lowering of total cholesterol values, it is such that a redistribution in the ratio of good (HDL) to bad (LDL) cholesterol occurs, usually moving values in an unfavorable direction. This would of course negate any positive effect that Oxandrolone might have on triglycerides or total cholesterol, and in fact make it a danger in terms of cardiac risk when taken for prolonged periods of time. Today we understand that as a group anabolic/androgenic steroids produce very unfavorable changes in lipid profiles, and are really not useful in disorders of lipid metabolism. As an oral c17 alpha alkylated steroid, Oxandrolone is even more risky to use than an injectable esterified injectable such as a testosterone or nandrolone in t regard.
Amount of any Oxandrolone types
On the black market, Oxandrolone has always been a hot item . Although the substance is again being manufactured in the U.S., don't count on seeing it much. The exorbitant price BTG is asking for Oxandrin precludes it from entering the black market in anyvolume. At the pharmacy, these tablets can cost over $4 each, a tremendous jump from the price Searle was selling it for a decade earlier. Before last year, this left the SPA version from Italy as the only version athletes did see regularly on the black market. They come 30 tabs to a box, in 2 foil and plastic strips of 15 each. The tablets usually sell for $1.2 each, which is much more reasonable than the U.S. item. This is a trusted item, but may still not be the most cost effective at this time. To cash in on the obvious high demand and low supply for Oxandrolone, a 2.5mg version was introduced a little closer to home, Mexico, by the firm Ttokkyo. These guys are working hard to introduce products that bodybuilders, I mean house pets, are going to have a high demand for. The 2.5mg product seemed to do very well, although more recently they have doubled to dosage on this item to 5mg per tablet. Both versions of the Ttokkyo product are still circulating at this time, come in plastic bottles of 100 tablets each, and offer the most steroid per dollar for a commercial product. Additionally, many athletes have found mail-order sources that carry generic preparations, often in 5mg and 10mg capsules, which may offer even better pricing. Thus far I have seen such drugs produced in Spain, France and Brazil. It is obviously difficult to determine if these are legitimate when purchasing, so there is risk involved.
